"Fatal Encounters" tells the stories of people in the wrong place at the wrong time. It traces the doomed relationships between victim and killer as their paths intertwine, setting the stage for a series of events that lead to murder. Each episode begins with the introduction of the protagonists as they go about their normal business, unaware of what's about to transpire. An on-screen clock counts down the victim's final hours, making it clear to viewers the decisions and actions that contribute to the victim falling into the killer's fatal trap. Interviews with people familiar with the cases also contribute to the stories.